The MIMOSA consortium gathers experts in different scientific fields from 6 laboratories and 1 industrial partner.

GPM – CNRS / University of Rouen Normandie – France [website]
CORIA – CNRS / University of Rouen Normandie – France [website]
Nonlinear Optical Spectroscopy Group – CNR-ISASI – Italy [website]
Bruno Kessler Foundation – University of Trento – Italy [website]
EnVI INSERM – University of Rouen Normandie – France [website]
Chalmers University of Technology – Gothenburg – Sweden [website]
Active Fiber Systems – Jena – Germany [website]
IMT – Bucharest – Romania [website]

Meet each partner and their researchers below.

GPM [CNRS – University of Rouen Normandie] FR

Pr. Angela Vella did her PhD at the University of Naples on non linear optics. After a post doc at the University of Montpellier and at the ENS de Cachan, she joined as assistant professor the GPM in 2005. She was involved in the pioneer work on the development of the atom probe tomography assisted by ultrafast laser pulses. Her work covers fundamentals of the field emission and laser-matter interaction. She co-authored more than 70 articles and have given more than 20 invited lectures along her career. She received the prize “Bronze medal” from CNRS in 2015 and the ‘Block Lecture Award’ attributed by IFES in 2012. Since 2016, she is full professor at the University of Rouen (France) and she is the coordinator of the MIMOSA project.

Dr Jonathan Houard (Research Engineer) obtained his thesis at the University of Rouen on laser/matter interaction in atom probe. After a post-doc on the coupling of TEM tomography and APT, he was recruited at the CNRS as a research engineer at the GPM. He is now in charge of laser APTs, amplified laser chains and laser experiments as well as the development and coupling of APT with optical measurements. He is the author or co-author of 45 articles in international peer-reviewed journals, one book chapter, and two patents. He has also been involved for 10 years in collaboration with CAMECA to improve APT and APT technology transfer.

Pr. Philippe Pareige did his PhD at GPM laboratory at Rouen Normandie University. He is a specialist in materials sciences and the use of atom probe tomography. He is leading research in physical metallurgy in the field of ageing of materials in nuclear reactors. He is the scientific director of the EQUIPEX Platform GENESIS (study of radioactive materials). He is also working on semiconductor nanodevices for light emission or solar cells. Recently he developed interdisciplinary activities between Physic and Health. How microscopies of physicists can help in the field of health! He has been Director of the GPM laboratory for 10 years (2012 – 2021).

Matteo De Tullio : « After my graduation at Liceo Classico “Quinto Orazio Flacco” in Bari, I undertook a three-year Bachelor’s Degree in Physics at the University of Bari “Aldo Moro”, obtained in July 2019. Afterwards, I attained my Master’s degree in Physics of Matter at the University of Padova. In October 2022, I obtained a PhD position in Physics in Rouen, where I will work as a member of the GPM (Groupe de Physique des Matériaux) within the MIMOSA project, which aims to extend the use of the new atomic probe assisted by terahertz pulses to biological materials encapsulated in sol-gel matrices. »

CORIA [CNRS – University of Rouen Normandie] FR

The CORIA‘s Optics and Lasers Department focuses its research on the development of advanced optical instrumentation and particularly on the development of high-performance ultrafast solid-state and fiber lasers and ultrafast metrology. This research group is led by Prof. Ammar Hideur, along with Dr. Thomas Godin and Dr. Pierre-Henry Hanzard. Within the MIMOSA project, the CORIA group aims at implementing high repetition rate pulsed THz sources based on different approaches (NIR and MIR wavelength ranges) such as two-color air plasma or optical rectification in nonlinear crystals, in collaboration with AFS Jena.

From left to right: Anna Martinez [PhD student], Benoît Barviau [Associate Professor], Alisson Rodrigues Da Paula [PhD student], Ammar Hideur [Professor], Thomas Godin [Associate Professor], Saïd Idlahcen [Research engineer], Armand Cervera [Master student], Pierre-Henry Hanzard [Associate Professor]

Prof. Andersson’s group [Chalmers Univ. of Technology] SE

Chalmers University of Technology in Gothenburg, Sweden, has a strong history of atom probe tomography (APT) research both in development of the methodology and instrumentation, as well as utilizing the technique in materials science. Traditionally, steels for various applications and zirconium alloys for use in nuclear reactors have been analysed, but recently analyses of bone-implant interfaces as well as biomolecules have been added to the list of materials. The strategy of embedding proteins in a silica matrix to form a durable material for atom probe tomography determination of a protein’s 3D structure was developed by researchers involved in the MIMOSA project at Chalmers. The contribution of Chalmers to MIMOSA will encompass further development of embedding methods for several biomolecules, for example studies of cell transmembrane proteins in their native form (objective 3). This will be performed together with expertise in material synthesis as well as protein production and purification at Chalmers. Biomolecules with relevance for pharmaceutical drug development will be identified in close collaboration with the pharmaceutical industry, and APT studies of these materials using commercial state of the art instruments (objective 4) aims to reveal the 4D structure of the biomolecules. The experimental data together with theoretical modelling developed by partners within MIMOSA will be crucial for understanding the interaction of the biomolecules with the matrix material, as well as the evaporation processes involved in APT. Additionally, comparison of the data obtained from commercial APT instruments with the newly developed instrument in the Mimosa project will provide insights into the unique properties and advantages of the THz laser assisted atom probe (objective 2).

From left to right: Associate professor Mattias Thuvander, Dr. Mats Hulander, Professor Martin Andersson and PhD candidate Gustav Eriksson. In the background, the new APT instrument, LEAP 6000 XR, which recently was installed at Chalmers is seen.

Active Fiber Systems [Jena] DE

Active Fiber Systems GmbH is located in Jena known as the ‘City of Photonics’ in Germany. Active Fiber Systems GmbH (AFS) is a technological leader for high-power femtosecond laser systems. Our employees have pushed the boundaries of what is possible over the last decade. Our solutions range from compact options all the way to complex high-power femtosecond laser beamlines with multiple output ports. All of our high-power laser systems are fully-based on fiber amplifier technology – developed in Jena, Germany. Fiber lasers enjoy an excellent reputation as power-scalable diode-pumped solid-state laser concept. Their immunity against thermo-optical issues is combined with efficiency, excellent performance and turnkey reliability. During the last two decades, ultra-short-pulse fiber-laser systems have been continuously improved in Jena’s research institutes (e.g. Fraunhofer IOF, Institute for Applied Physics). The laboratory results are ground-breaking; several world records in performance are held in Jena. Today, as a spin-off, AFS even surpassed the performance of these research laser systems in many parameters and has become a world-wide technological leader in many fields of high-power laser development. The self-defined mission of AFS is to transfer laboratory setups with world-record parameters to reliable laser systems suitable for scientific and industrial applications. We have been selling high-power fiber lasers for more than a decade now and continue to push the boundaries of what is possible.

The AFS team in Jena, Germany

Nonlinear Optical Spectroscopy Group [CNR – ISASI] IT

The Nonlinear Optical Spectroscopy (NOS) Group is based in the Physics Department of the Federico II University of Naples, one of the largest and oldest research universities in Italy. The group was born as a joint venture between researchers of the Italian National Council for Research (CNR) and of the Physics Department.

We investigate various aspects of light-matter interaction by using ultrafast (femtosecond) intense laser pulses, with particular emphasis on spatially structured systems. The processes that are nonlinear in the optical field add new potentialities to standard optical spectroscopy, which has always been an invaluable experimental tool for elucidating fundamental mechanisms in soft and condensed matter physics. For instance, by exploiting second-order processes we investigate surface and interface properties with sub-nanometer resolution (second harmonic generation – SHG). Another example is given by two colors Four-Wave-Mixing in air, which we exploit to coherently generate broad-band single-cycle THz pulses, so to expand our spectroscopic capability to the very-far infrared region. The THz pulses generated in this way are extremely intense, thus enabling the observation of nonlinear optical effects until now investigated only in the visible range of the electromagnetic spectrum. This is the case of the coherent THz Hyper-Raman (THYR) effect, which we have very recently discovered (see figure). 

We apply our spectroscopic tools to a large variety of materials with a special focus in recent years on the hetero-structures of strongly correlated transition-metal oxides, ultrathin ferroelectric films, laser-treated diamond for THz applications and ionic liquids. We are also interested in complex-structured singular light beams or photons, such as those carrying orbital angular momentum, or having a space-variant polarization, and in their interaction with matter.

European Centre for Theoretical Studies in Nuclear Physics and Related Areas [Bruno Kessler Foundation – University of Trento] IT

FBK-ECT is renowned for its expertise in computing related to protein structures and their interaction with matrices, combined with investigation on electronic structures. Within the MIMOSA project, the group will work on the theoretical interpretation of TAP analysis. Their objective is to develop quantitative understanding via mathematical and computational modelling of the structure and dynamics of proteins, also upon application of intense static electric fields and THz laser pulses.

EnVI group [INSERM – University of Rouen Normandie] FR

Inserm-EnVI has a long experience on cardiovascular diseases, opening avenue for collaborations with medical professionals when our prototypes will be mature enough. The objective of the MIMOSA project is to provide a proof of concept of spatial and chemical characterization of relevant biological samples at the nanoscale. In this context, the Inserm-EnVI unit will provide different human and murine biological samples of increasing structural complexity related to the cardiovascular system: liposomes (empty and with encapsulated drugs), recombinant proteins (alone and in the presence of a substrate/agonist/inhibitor), lipoproteins, exosomes and purified cell and mitochondrial membrane proteins. Once obtained, these samples will be submitted to TAP analysis.

National Institute for Research and Development in Microtechnologies [IMT Bucharest] RO

IMT-Bucharest is a  national institute, one of the main Romanian R&D organization specialized in micro-nano-bio-technologies and nano-electronics. The main research fields are in closed connections to 4  KETs (Key Enabling Technologies): micro-nanoelectronics, photonics, nanotechnology, advanced materials.

Centre for Micro- and NAnoFABrication ( – IMT-MINAFAB infrastructure, ISO 9001 certified, contains a key unit, the „Facility for micro-nanostructuring of devices and systems”, unique in Romania.

Within the MIMOSA project the IMT group aims at implementing pulse shaping protocols for tailoring the 4D spatio-temporal properties of THz pulses with complex optical elements in collaboration with CNR partner.

First row: Cristian Kusko – Senior Researcher, Oana Tutunaru – Scientific Researcher , Pericle Varasteanu – Junior Researcher, Rebeca Tudor  – Scientific Researcher – Team Leader
Second row: Dan Vasilache -Senior Researcher  Dana Cristea -Senior Researcher, Damir Mladenovic – PhD Student, Andrei Avram – Senior Researcher, Viorel Avramescu – Scientific Researcher, Mihai Kusko – Senior Researcher
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